Download e-book for iPad: Amyotrophic Lateral Sclerosis and the Frontotemporal by Michael J. Strong

By Michael J. Strong

ISBN-10: 0199590672

ISBN-13: 9780199590674

During the last ten years, there was an expanding reputation that syndromes of frontotemporal disorder (FTD) are a typical incidence in sufferers with amyotrophic lateral sclerosis (ALS). Such syndromes will be found in as many as 60% of sufferers with ALS. Conversely, the prevalence of motor neuron disorder in sufferers with clinically natural frontotemporal dementia is more and more famous. this means that to a point there are overlapping syndromes within which either ALS and FTD ensue in the similar person.

This quantity summarizes the advances in our knowing of those problems, in addition to the capability courting among the 2. Key themes contain advances in our skill to clinically describe the frontotemporal syndromes, preclinical detection, neuroimaging, and genetics. The exploding box of latest markers in neuropathology is tested, as is the position of latest genetic mutations in DNA/RNA delivery platforms. This publication is the basic reference textual content for this subject, and may be of curiosity to neurologists and neurological trainees with a scientific or examine curiosity within the FTDs or ALS, neuropsychologists, neuropathologists, and researchers.

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Additional info for Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias

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Epidemiologic investigations of amyotrophic lateral sclerosis. 1. Preliminary report on geographic distributions, with special reference to the Marianas Islands, including clinical and pathological observations. Neurology, 4, 355–378, 438–448. 11. Garruto RM. (2006). A commentary on neuronal degeneration and cell death in Guam ALS and PD: an evolutionary process of understanding. Curr Alzheimer Res, 3, 397–401. 12. Charcot JM, Joffroy A. (1869). Deux cas d’atrophie musculaire progressive avec lésions de la substance grise et des faisceaux antérolateraux de la moëlle épinière.

Strong MJ. (2001). The evidence for ALS as a multisystems disorder of limited phenotypic expression. Can J Neurol Sci, 28, 283–298. 20. Duchenne (De Boulogne). (1860). Paralysie musculaire progressive de la langue, du voile du palais et des levres; affection non encore decrite comme espece morbide distincte. Arch Gen Med, 16, 283–296. 21. Aran FA. (1850). Recherches sur une maladie non encore décrite du systéme musculaire (atrophie musculaire progressive). Arch Gén de Méd, 24, 5–35. 22. Aran FA.

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Amyotrophic Lateral Sclerosis and the Frontotemporal Dementias by Michael J. Strong


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